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Tryptophanyl tRNA synthetase (WARS) (NM_173701) Human Recombinant Protein

Product Specifications

Background

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

GAMMA-2; HMN9; IFI53; IFP53; WARS

Gene ID

7453

UniProt

P23381, A0A024R6K8

Accession Number mRNA

NM_173701

Chromosomal Location

14q32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Aminoacyl-tRNA biosynthesis, Tryptophan metabolism

Field of Research

Aminoacyl-tRNA biosynthesis, Tryptophan metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

53 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

WARS

Species

Human

Protein ID

NP_776049

Overview

Recombinant protein of human tryptophanyl-tRNA synthetase (WARS), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7453

Uniprot URL

https://www.uniprot.org/uniprot/P23381

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_173701

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_776049

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