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ASD3 (MYH6) (NM_002471) Human Recombinant Protein

Product Specifications

Background

Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Feb 2017]

Synonyms

Alpha-MHC; ASD3; CMD1EE; CMH14; MYHC; MYHCA; SSS3

Gene ID

4624

UniProt

P13533

Accession Number mRNA

NM_002471

Chromosomal Location

14q11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Tight junction, Viral myocarditis

Field of Research

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Tight junction, Viral myocarditis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

223.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MYH6

Species

Human

Protein ID

NP_002462

Overview

Purified recombinant protein of Homo sapiens myosin, heavy chain 6, cardiac muscle, alpha (MYH6)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4624

Uniprot URL

https://www.uniprot.org/uniprot/P13533

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002471

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002462

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