Glycerol kinase (GK) (NM_000167) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Overview
Recombinant protein of human glycerol kinase (GK), transcript variant 2
Synonyms
GK1; GKD
Gene ID
2710
UniProt
P32189, B4DH54
Accession Number mRNA
NM_000167
Chromosomal Location
Xp21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glycerolipid metabolism, Metabolic pathways, PPAR signaling pathway
Field of Research
Glycerolipid metabolism, Metabolic pathways, PPAR signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
57.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GK
Species
Human
Protein ID
NP_000158
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2710
Uniprot URL
https://www.uniprot.org/uniprot/P32189
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000167
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000158
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