BCS1L (NM_001079866) Human Recombinant Protein
Product Specifications
Background
This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described. [provided by RefSeq, Jan 2016]
Synonyms
BCS; BCS1; BJS; FLNMS; GRACILE; h-BCS; h-BCS1; Hs.6719; MC3DN1; PTD
Gene ID
617
UniProt
Q9Y276, A0A024R445
Accession Number mRNA
NM_001079866
Chromosomal Location
2q35
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
47.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BCS1L
Species
Human
Protein ID
NP_001073335
Overview
Recombinant protein of human BCS1-like (yeast) (BCS1L), nuclear gene encoding mitochondrial protein, transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/617
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y276
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001079866
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001073335
Curated Selection
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