IFITM5 (NM_001025295) Human Recombinant Protein
Product Specifications
Background
This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195) . [provided by RefSeq, Aug 2012]
Overview
Recombinant protein of human interferon induced transmembrane protein 5 (IFITM5)
Synonyms
BRIL; DSPA1; fragilis4; Hrmp1; OI5
Gene ID
387733
UniProt
A6NNB3
Accession Number mRNA
NM_001025295
Chromosomal Location
11p15.5
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
14.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IFITM5
Species
Human
Protein ID
NP_001020466
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/387733
Uniprot URL
https://www.uniprot.org/uniprot/A6NNB3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001025295
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001020466
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