Nesprin 2 (SYNE2) (NM_182910) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms
EDMD5; KASH2; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; TROPH
Gene ID
23224
UniProt
Q8WXH0
Accession Number mRNA
NM_182910
Chromosomal Location
14q23.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
48 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SYNE2
Species
Human
Protein ID
NP_878914
Overview
Recombinant protein of human spectrin repeat containing, nuclear envelope 2 (SYNE2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23224
Uniprot URL
https://www.uniprot.org/uniprot/Q8WXH0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_182910
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_878914
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