What is the catalog number for STAT1 (NM_007315) Human Recombinant Protein?

The catalog number for STAT1 (NM_007315) Human Recombinant Protein is PH36264M5.

What sizes are available for STAT1 (NM_007315) Human Recombinant Protein?

STAT1 (NM_007315) Human Recombinant Protein is available in the following size(s): 20 µg.

Is STAT1 (NM_007315) Human Recombinant Protein in stock?

STAT1 (NM_007315) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

STAT1 (NM_007315) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]

Overview

Recombinant protein of human signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha

Synonyms

CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Gene ID

6772

UniProt

P42224

Accession Number mRNA

NM_007315

Chromosomal Location

2q32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

Field of Research

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

27796300

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

87.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.