ERC1 (NM_178040) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t (10;12) (q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms
Cast2; ELKS; ERC-1; RAB6IP2
Gene ID
23085
UniProt
Q8IUD2
Accession Number mRNA
NM_178040
Chromosomal Location
12p13.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
127.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ERC1
Species
Human
Protein ID
NP_829884
Overview
Purified recombinant protein of Homo sapiens ELKS/RAB6-interacting/CAST family member 1 (ERC1), transcript variant epsilon
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23085
Uniprot URL
https://www.uniprot.org/uniprot/Q8IUD2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178040
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_829884
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