USP7 (NM_003470) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
Synonyms
HAFOUS; HAUSP; TEF1
Gene ID
7874
UniProt
Q93009, Q6U8A4
Accession Number mRNA
NM_003470
Chromosomal Location
16p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
128.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
USP7
Species
Human
Protein ID
NP_003461
Overview
Recombinant protein of human ubiquitin specific peptidase 7 (herpes virus-associated) (USP7)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7874
Uniprot URL
https://www.uniprot.org/uniprot/Q93009
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003470
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003461
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