OPHN1 (NM_002547) Human Recombinant Protein
Product Specifications
Background
This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked cognitive disability with cerebellar hypoplasia and distinctive facial dysmorhphism. [provided by RefSeq, Jul 2008]
Synonyms
ARHGAP41; MRX60; OPN1
Gene ID
4983
UniProt
O60890
Accession Number mRNA
NM_002547
Chromosomal Location
Xq12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
91.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
OPHN1
Species
Human
Protein ID
NP_002538
Overview
Recombinant protein of human oligophrenin 1 (OPHN1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4983
Uniprot URL
https://www.uniprot.org/uniprot/O60890
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002547
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002538
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