GCKR (NM_001486) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY) . [provided by RefSeq, Jul 2008]
Synonyms
FGQTL5; GKRP
Gene ID
2646
UniProt
Q14397, A0A0C4DFN2
Accession Number mRNA
NM_001486
Chromosomal Location
2p23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
68.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GCKR
Species
Human
Protein ID
NP_001477
Overview
Recombinant protein of human glucokinase (hexokinase 4) regulator (GCKR)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2646
Uniprot URL
https://www.uniprot.org/uniprot/Q14397
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001486
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001477
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