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CYP2A7 (NM_030589) Human Recombinant Protein

Selected Variant

PH36175M5

Size: 20 µg

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human cytochrome P450, family 2, subfamily A, polypeptide 7 (CYP2A7), transcript variant 2

Synonyms

CPA7; CPAD; CYP2A; CYPIIA7; P450-IIA4

Gene ID

1549

UniProt

P20853, F8W816

Accession Number mRNA

NM_030589

Chromosomal Location

19q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism

Field of Research

Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, P450, Transmembrane

Molecular Weight

50.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CYP2A7

Species

Human

Protein ID

NP_085079

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1549

Uniprot URL

https://www.uniprot.org/uniprot/P20853

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030589

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_085079

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