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RS1 (NM_000330) Human Recombinant Protein

Selected Variant

PH36170M5

Size: 20 µg

Product Specifications

Background

This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008]

Overview

Recombinant protein of human retinoschisin 1 (RS1)

Synonyms

RS; XLRS1

Gene ID

6247

UniProt

O15537

Accession Number mRNA

NM_000330

Chromosomal Location

Xp22.13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

23 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RS1

Species

Human

Protein ID

NP_000321

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6247

Uniprot URL

https://www.uniprot.org/uniprot/O15537

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000330

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000321

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