RS1 (NM_000330) Human Recombinant Protein
Selected Variant
PH36170M5
Size: 20 µg
Product Specifications
Background
This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008]
Overview
Recombinant protein of human retinoschisin 1 (RS1)
Synonyms
RS; XLRS1
Gene ID
6247
UniProt
O15537
Accession Number mRNA
NM_000330
Chromosomal Location
Xp22.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
23 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RS1
Species
Human
Protein ID
NP_000321
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6247
Uniprot URL
https://www.uniprot.org/uniprot/O15537
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000330
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000321
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