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SRGAP3 (NM_014850) Human Recombinant Protein

Product Specifications

Background

GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.[UniProtKB/Swiss-Prot Function]

Synonyms

ARHGAP14; MEGAP; SRGAP2; WRP

Gene ID

9901

UniProt

O43295

Accession Number mRNA

NM_014850

Chromosomal Location

3p25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

124.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SRGAP3

Species

Human

Protein ID

NP_055665

Overview

Purified recombinant protein of Homo sapiens SLIT-ROBO Rho GTPase activating protein 3 (SRGAP3), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9901

Uniprot URL

https://www.uniprot.org/uniprot/O43295

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014850

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055665

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