Cyclophilin E (PPIE) (NM_006112) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]
Overview
Recombinant protein of human peptidylprolyl isomerase E (cyclophilin E) (PPIE), transcript variant 1
Synonyms
CYP-33; CYP33
Gene ID
10450
UniProt
Q9UNP9
Accession Number mRNA
NM_006112
Chromosomal Location
1p34.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
33.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPIE
Species
Human
Protein ID
NP_006103
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10450
Uniprot URL
https://www.uniprot.org/uniprot/Q9UNP9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006112
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006103
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