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CNBP (NM_003418) Human Recombinant Protein

Selected Variant

PH36133M5

Size: 20 µg

Product Specifications

Background

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]

Overview

Recombinant protein of human CCHC-type zinc finger, nucleic acid binding protein (CNBP), transcript variant 3

Synonyms

CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9

Gene ID

7555

UniProt

P62633, A0A0S2Z4K2

Accession Number mRNA

NM_003418

Chromosomal Location

3q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

19.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CNBP

Species

Human

Protein ID

NP_003409

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7555

Uniprot URL

https://www.uniprot.org/uniprot/P62633

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003418

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003409

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