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RGS11 (NM_003834) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]

Overview

Recombinant protein of human regulator of G-protein signaling 11 (RGS11), transcript variant 2

Synonyms

RS11

Gene ID

8786

UniProt

O94810

Accession Number mRNA

NM_003834

Chromosomal Location

16p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

50.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RGS11

Species

Human

Protein ID

NP_003825

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8786

Uniprot URL

https://www.uniprot.org/uniprot/O94810

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003834

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003825

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