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CA5A (NM_001739) Human Recombinant Protein

Product Specifications

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human carbonic anhydrase VA, mitochondrial (CA5A), nuclear gene encoding mitochondrial protein

Synonyms

CA5; CA5AD; CAV; CAVA; GS1-21A4.1

Gene ID

763

UniProt

P35218

Accession Number mRNA

NM_001739

Chromosomal Location

16q24.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Nitrogen metabolism

Field of Research

Nitrogen metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

30.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CA5A

Species

Human

Protein ID

NP_001730

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/763

Uniprot URL

https://www.uniprot.org/uniprot/P35218

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001739

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001730

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