CA5A (NM_001739) Human Recombinant Protein
Product Specifications
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
Synonyms
CA5; CA5AD; CAV; CAVA; GS1-21A4.1
Gene ID
763
UniProt
P35218
Accession Number mRNA
NM_001739
Chromosomal Location
16q24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Nitrogen metabolism
Field of Research
Nitrogen metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
30.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CA5A
Species
Human
Protein ID
NP_001730
Overview
Recombinant protein of human carbonic anhydrase VA, mitochondrial (CA5A), nuclear gene encoding mitochondrial protein
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/763
Uniprot URL
https://www.uniprot.org/uniprot/P35218
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001739
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001730
Curated Selection
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