SETD3 (NM_032233) Human Recombinant Protein
Product Specifications
Background
Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30526847, PubMed:30626964, PubMed:30785395) . Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964) . Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964, PubMed:30785395) .[UniProtKB/Swiss-Prot Function]
Synonyms
C14orf154; hSETD3
Gene ID
84193
UniProt
Q86TU7, A0A024R6K3
Accession Number mRNA
NM_032233
Chromosomal Location
14q32.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
67.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SETD3
Species
Human
Protein ID
NP_115609
Overview
Recombinant protein of human SET domain containing 3 (SETD3), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84193
Uniprot URL
https://www.uniprot.org/uniprot/Q86TU7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032233
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_115609
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