Calcitonin (CALCA) (NM_001741) Human Recombinant Protein
Product Specifications
Background
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
Synonyms
CALC1; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT
Gene ID
796
UniProt
P01258
Accession Number mRNA
NM_001741
Chromosomal Location
11p15.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
12.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CALCA
Species
Human
Protein ID
NP_001732
Overview
Recombinant protein of human calcitonin-related polypeptide alpha (CALCA), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/796
Uniprot URL
https://www.uniprot.org/uniprot/P01258
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001741
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001732
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