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DAB1 (NM_021080) Human Recombinant Protein

Product Specifications

Background

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]

Overview

Recombinant protein of human disabled homolog 1 (Drosophila) (DAB1)

Synonyms

SCA37

Gene ID

1600

UniProt

O75553

Accession Number mRNA

NM_021080

Chromosomal Location

1p32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

59.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DAB1

Species

Human

Protein ID

NP_066566

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1600

Uniprot URL

https://www.uniprot.org/uniprot/O75553

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021080

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_066566

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