PYDC2 (NM_001083308) Human Recombinant Protein
Product Specifications
Background
May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome (PubMed:17339483, PubMed:17178784) . May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA (PubMed:17339483, PubMed:24871464) .[UniProtKB/Swiss-Prot Function]
Synonyms
CPOP2; POP2
Gene ID
152138
UniProt
Q56P42
Accession Number mRNA
NM_001083308
Chromosomal Location
3q28
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
10.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PYDC2
Species
Human
Protein ID
NP_001076777
Overview
Recombinant protein of human pyrin domain containing 2 (PYDC2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/152138
Uniprot URL
https://www.uniprot.org/uniprot/Q56P42
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001083308
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001076777
Curated Selection
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