PYDC2 (NM_001083308) Human Recombinant Protein

Product Specifications

Background

May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome (PubMed:17339483, PubMed:17178784) . May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA (PubMed:17339483, PubMed:24871464) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human pyrin domain containing 2 (PYDC2)

Synonyms

CPOP2; POP2

Gene ID

152138

UniProt

Q56P42

Accession Number mRNA

NM_001083308

Chromosomal Location

3q28

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

10.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.