HMGA2 (NM_003484) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms
BABL; HMGI-C; HMGIC; LIPO; SRS5; STQTL9
Gene ID
8091
UniProt
P52926
Accession Number mRNA
NM_003484
Chromosomal Location
12q14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
11.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMGA2
Species
Human
Protein ID
NP_003475
Overview
Recombinant protein of human high mobility group AT-hook 2 (HMGA2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8091
Uniprot URL
https://www.uniprot.org/uniprot/P52926
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003484
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003475
Curated Selection
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