CLN5 (NM_006493) Human Recombinant Protein
Product Specifications
Background
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008]
Synonyms
NCL
Gene ID
1203
UniProt
O75503, A0A024R644
Accession Number mRNA
NM_006493
Chromosomal Location
13q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Lysosome
Field of Research
Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
46.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLN5
Species
Human
Protein ID
NP_006484
Overview
Recombinant protein of human ceroid-lipofuscinosis, neuronal 5 (CLN5)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1203
Uniprot URL
https://www.uniprot.org/uniprot/O75503
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006493
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006484
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