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CABYR (NM_012189) Human Recombinant Protein

Product Specifications

Background

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Overview

Recombinant protein of human calcium binding tyrosine- (Y) -phosphorylation regulated (CABYR), transcript variant 1

Synonyms

CABYRa; CABYRc; CABYRc/d; CABYRe; CBP86; CT88; FSP-2; FSP2

Gene ID

26256

UniProt

O75952, A0A024RC21

Accession Number mRNA

NM_012189

Chromosomal Location

18q11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

52.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CABYR

Species

Human

Protein ID

NP_036321

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/26256

Uniprot URL

https://www.uniprot.org/uniprot/O75952

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012189

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036321

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