KIST (UHMK1) (NM_175866) Human Recombinant Protein
Product Specifications
Background
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Synonyms
KIS; KIST; P-CIP2
Gene ID
127933
UniProt
Q8TAS1
Accession Number mRNA
NM_175866
Chromosomal Location
1q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
46.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UHMK1
Species
Human
Protein ID
NP_787062
Overview
Recombinant protein of human U2AF homology motif (UHM) kinase 1 (UHMK1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/127933
Uniprot URL
https://www.uniprot.org/uniprot/Q8TAS1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_175866
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_787062
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