What is the catalog number for UBE3C (NM_014671) Human Recombinant Protein?

The catalog number for UBE3C (NM_014671) Human Recombinant Protein is PH35981M5.

What sizes are available for UBE3C (NM_014671) Human Recombinant Protein?

UBE3C (NM_014671) Human Recombinant Protein is available in the following size(s): 20 µg.

Is UBE3C (NM_014671) Human Recombinant Protein in stock?

UBE3C (NM_014671) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

UBE3C (NM_014671) Human Recombinant Protein

Product Specifications

Background

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human ubiquitin protein ligase E3C (UBE3C)

Synonyms

HECTH2

Gene ID

9690

UniProt

Q15386

Accession Number mRNA

NM_014671

Chromosomal Location

7q36.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

123.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.