Gastrin Releasing Peptide (GRP) (NM_001012513) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Overview
Purified recombinant protein of Homo sapiens gastrin-releasing peptide (GRP), transcript variant 3
Synonyms
BN; GRP-10; preproGRP; proGRP
Gene ID
2922
UniProt
P07492
Accession Number mRNA
NM_001012513
Chromosomal Location
18q21.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
12.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GRP
Species
Human
Protein ID
NP_001012531
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2922
Uniprot URL
https://www.uniprot.org/uniprot/P07492
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001012513
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001012531
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