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Gastrin Releasing Peptide (GRP) (NM_001012513) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Overview

Purified recombinant protein of Homo sapiens gastrin-releasing peptide (GRP), transcript variant 3

Synonyms

BN; GRP-10; preproGRP; proGRP

Gene ID

2922

UniProt

P07492

Accession Number mRNA

NM_001012513

Chromosomal Location

18q21.32

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

12.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GRP

Species

Human

Protein ID

NP_001012531

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2922

Uniprot URL

https://www.uniprot.org/uniprot/P07492

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001012513

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001012531

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