Adenylate Kinase 1 (AK1) (NM_000476) Human Recombinant Protein
Product Specifications
Background
This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human adenylate kinase 1 (AK1)
Synonyms
HTL-S-58j
Gene ID
203
UniProt
P00568, Q6FGX9
Accession Number mRNA
NM_000476
Chromosomal Location
9q34.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Purine metabolism
Field of Research
Metabolic pathways, Purine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
21.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AK1
Species
Human
Protein ID
NP_000467
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/203
Uniprot URL
https://www.uniprot.org/uniprot/P00568
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000476
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000467
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