Synaptojanin 2 (SYNJ2) (NM_003898) Human Recombinant Protein
Product Specifications
Background
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Overview
Recombinant protein of human synaptojanin 2 (SYNJ2)
Synonyms
INPP5H
Gene ID
8871
UniProt
O15056, B4DG94
Accession Number mRNA
NM_003898
Chromosomal Location
6q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
Field of Research
Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
165.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SYNJ2
Species
Human
Protein ID
NP_003889
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8871
Uniprot URL
https://www.uniprot.org/uniprot/O15056
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003898
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003889
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