RGS11 (NM_183337) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
Synonyms
RS11
Gene ID
8786
UniProt
O94810, Q4TT70
Accession Number mRNA
NM_183337
Chromosomal Location
16p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
52.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RGS11
Species
Human
Protein ID
NP_899180
Overview
Recombinant protein of human regulator of G-protein signaling 11 (RGS11), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8786
Uniprot URL
https://www.uniprot.org/uniprot/O94810
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_183337
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_899180
Curated Selection
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