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Protein cornichon homolog 2 (CNIH2) (NM_182553) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Overview

Recombinant protein of human cornichon homolog 2 (Drosophila) (CNIH2)

Synonyms

CNIH-2; Cnil

Gene ID

254263

UniProt

Q6PI25

Accession Number mRNA

NM_182553

Chromosomal Location

11q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

18.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CNIH2

Species

Human

Protein ID

NP_872359

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/254263

Uniprot URL

https://www.uniprot.org/uniprot/Q6PI25

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_182553

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_872359

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