DAP Kinase 1 (DAPK1) (NM_004938) Human Recombinant Protein
Product Specifications
Background
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Synonyms
DAPK; ROCO3
Gene ID
1612
UniProt
P53355, B4DHI4
Accession Number mRNA
NM_004938
Chromosomal Location
9q21.33
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Bladder cancer, Pathways in cancer
Field of Research
Bladder cancer, Pathways in cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
159.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DAPK1
Species
Human
Protein ID
NP_004929
Overview
Recombinant protein of human death-associated protein kinase 1 (DAPK1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1612
Uniprot URL
https://www.uniprot.org/uniprot/P53355
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004938
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004929
Curated Selection
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