DAP Kinase 1 (DAPK1) (NM_004938) Human Recombinant Protein

Product Specifications

Background

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Overview

Recombinant protein of human death-associated protein kinase 1 (DAPK1)

Synonyms

DAPK; ROCO3

Gene ID

1612

UniProt

P53355, B4DHI4

Accession Number mRNA

NM_004938

Chromosomal Location

9q21.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Bladder cancer, Pathways in cancer

Field of Research

Bladder cancer, Pathways in cancer

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

159.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.