PLEKHM1 (NM_014798) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6) . Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

Overview

Recombinant protein of human pleckstrin homology domain containing, family M (with RUN domain) member 1 (PLEKHM1)

Synonyms

AP162; B2; OPTA3; OPTB6

Gene ID

9842

UniProt

Q9Y4G2

Accession Number mRNA

NM_014798

Chromosomal Location

17q21.31

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

117.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.