GRIN3A (NM_133445) Human Recombinant Protein

Product Specifications

Background

This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human glutamate receptor, ionotropic, N-methyl-D-aspartate 3A (GRIN3A)

Synonyms

GluN3A; NMDAR-L; NMDAR3A; NR3A

Gene ID

116443

UniProt

Q8TCU5

Accession Number mRNA

NM_133445

Chromosomal Location

9q31.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Neuroactive ligand-receptor interaction

Field of Research

Neuroactive ligand-receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane

Molecular Weight

125.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.