ASH2L (NM_004674) Human Recombinant Protein
Product Specifications
Background
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.[UniProtKB/Swiss-Prot Function]
Synonyms
ASH2; ASH2L1; ASH2L2; Bre2
Gene ID
9070
UniProt
Q9UBL3
Accession Number mRNA
NM_004674
Chromosomal Location
8p11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
68.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ASH2L
Species
Human
Protein ID
NP_004665
Overview
Recombinant protein of human ash2 (absent, small, or homeotic) -like (Drosophila) (ASH2L), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9070
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBL3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004674
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004665
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