EDA (NM_001005610) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human ectodysplasin A (EDA), transcript variant 3
Synonyms
ECTD1; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED
Gene ID
1896
UniProt
Q92838
Accession Number mRNA
NM_001005610
Chromosomal Location
Xq13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
19 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EDA
Species
Human
Protein ID
NP_001005610
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1896
Uniprot URL
https://www.uniprot.org/uniprot/Q92838
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001005610
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001005610
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