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EDA (NM_001005610) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ectodysplasin A (EDA), transcript variant 3

Synonyms

ECTD1; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED

Gene ID

1896

UniProt

Q92838

Accession Number mRNA

NM_001005610

Chromosomal Location

Xq13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein, Transmembrane

Molecular Weight

19 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EDA

Species

Human

Protein ID

NP_001005610

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1896

Uniprot URL

https://www.uniprot.org/uniprot/Q92838

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001005610

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001005610

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