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BAT3 (BAG6) (NM_080703) Human Recombinant Protein

Product Specifications

Background

This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

BAG-6; BAT3; D6S52E; G3

Gene ID

7917

UniProt

P46379, A0A1U9X7A6

Accession Number mRNA

NM_080703

Chromosomal Location

6p21.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency

Molecular Weight

118.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BAG6

Species

Human

Protein ID

NP_542434

Overview

Recombinant protein of human HLA-B associated transcript 3 (BAT3), transcript variant 3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7917

Uniprot URL

https://www.uniprot.org/uniprot/P46379

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_080703

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_542434

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