CGK2 (PRKG2) (NM_006259) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical. [provided by RefSeq, May 2018]

Overview

Recombinant protein of human protein kinase, cGMP-dependent, type II (PRKG2)

Synonyms

CGK2; cGKII; PKG2; PRKGR2

Gene ID

5593

UniProt

Q13237, A0A140VJM3

Accession Number mRNA

NM_006259

Chromosomal Location

4q21.21

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Gap junction, Long-term depression, Olfactory transduction

Field of Research

Gap junction, Long-term depression, Olfactory transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

87.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.