CGK2 (PRKG2) (NM_006259) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical. [provided by RefSeq, May 2018]
Synonyms
CGK2; cGKII; PKG2; PRKGR2
Gene ID
5593
UniProt
Q13237, A0A140VJM3
Accession Number mRNA
NM_006259
Chromosomal Location
4q21.21
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Gap junction, Long-term depression, Olfactory transduction
Field of Research
Gap junction, Long-term depression, Olfactory transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
87.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRKG2
Species
Human
Protein ID
NP_006250
Overview
Recombinant protein of human protein kinase, cGMP-dependent, type II (PRKG2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5593
Uniprot URL
https://www.uniprot.org/uniprot/Q13237
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006259
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006250
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