FTO (NM_001080432) Human Recombinant Protein
Product Specifications
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Synonyms
ALKBH9; BMIQ14; GDFD
Gene ID
79068
UniProt
Q9C0B1, B3KU60, Q99770
Accession Number mRNA
NM_001080432
Chromosomal Location
16q12.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
58.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FTO
Species
Human
Protein ID
NP_001073901
Overview
Recombinant protein of human fat mass and obesity associated (FTO)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79068
Uniprot URL
https://www.uniprot.org/uniprot/Q9C0B1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001080432
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001073901
Curated Selection
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