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SPHKAP (NM_030623) Human Recombinant Protein

Product Specifications

Background

Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Homo sapiens SPHK1 interactor, AKAP domain containing (SPHKAP), transcript variant 2

Synonyms

SKIP

Gene ID

80309

UniProt

Q2M3C7

Accession Number mRNA

NM_030623

Chromosomal Location

2q36.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

183.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SPHKAP

Species

Human

Protein ID

NP_085126

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/80309

Uniprot URL

https://www.uniprot.org/uniprot/Q2M3C7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030623

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_085126

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