SPHKAP (NM_030623) Human Recombinant Protein
Product Specifications
Background
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Homo sapiens SPHK1 interactor, AKAP domain containing (SPHKAP), transcript variant 2
Synonyms
SKIP
Gene ID
80309
UniProt
Q2M3C7
Accession Number mRNA
NM_030623
Chromosomal Location
2q36.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
183.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SPHKAP
Species
Human
Protein ID
NP_085126
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80309
Uniprot URL
https://www.uniprot.org/uniprot/Q2M3C7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030623
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_085126
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