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PRX (NM_020956) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein) . Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]

Synonyms

CMT4F

Gene ID

57716

UniProt

Q9BXM0

Accession Number mRNA

NM_020956

Chromosomal Location

19q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

15.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PRX

Species

Human

Protein ID

NP_066007

Overview

Recombinant protein of human periaxin (PRX), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57716

Uniprot URL

https://www.uniprot.org/uniprot/Q9BXM0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_020956

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_066007

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