PRX (NM_020956) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein) . Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]
Synonyms
CMT4F
Gene ID
57716
UniProt
Q9BXM0
Accession Number mRNA
NM_020956
Chromosomal Location
19q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
15.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRX
Species
Human
Protein ID
NP_066007
Overview
Recombinant protein of human periaxin (PRX), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57716
Uniprot URL
https://www.uniprot.org/uniprot/Q9BXM0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020956
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_066007
Curated Selection
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