VAV2 (NM_003371) Human Recombinant Protein
Product Specifications
Background
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Synonyms
VAV-2
Gene ID
7410
UniProt
P52735
Accession Number mRNA
NM_003371
Chromosomal Location
9q34.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway
Field of Research
B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28712859
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
96.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VAV2
Species
Human
Protein ID
NP_003362
Overview
Recombinant protein of human vav 2 guanine nucleotide exchange factor (VAV2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7410
Uniprot URL
https://www.uniprot.org/uniprot/P52735
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003371
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003362
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