PTOP (ACD) (NM_022914) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]
Synonyms
PIP1; PTOP; TINT1; TPP1
Gene ID
65057
UniProt
Q96AP0, A0A5F9ZCY9
Accession Number mRNA
NM_022914
Chromosomal Location
16q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
57.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACD
Species
Human
Protein ID
NP_075065
Overview
Recombinant protein of human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/65057
Uniprot URL
https://www.uniprot.org/uniprot/Q96AP0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022914
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075065
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