PYCR1 (NM_153824) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Overview

Recombinant protein of human pyrroline-5-carboxylate reductase 1 (PYCR1), transcript variant 2

Synonyms

ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR

Gene ID

5831

UniProt

P32322, Q8TBX0

Accession Number mRNA

NM_153824

Chromosomal Location

17q25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Arginine and proline metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

33.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.