RAD1 (NM_002853) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]
Synonyms
HRAD1; REC1
Gene ID
5810
UniProt
O60671, A0A024R045
Accession Number mRNA
NM_002853
Chromosomal Location
5p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
31.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RAD1
Species
Human
Protein ID
NP_002844
Overview
Recombinant protein of human RAD1 homolog (S. pombe) (RAD1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5810
Uniprot URL
https://www.uniprot.org/uniprot/O60671
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002853
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002844
Curated Selection
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